SKU: 74327397550

PDGFRAlpha (5D1) Mouse mAb

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Description

PDGFRAlpha (5D1) Mouse mAbPlatelet derived growth factor (PDGF) family proteins exist as several disulphide bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor Alpha (PDGFRAlpha) and PDGF receptor Beta (PDGFRBeta). PDGFRAlpha and PDGFRBeta can each form heterodimers with EGFR, which is also activated by PDGF. Various cells differ in the total number of

Platelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor Alpha (PDGFRAlpha) and PDGF receptor Beta (PDGFRBeta). PDGFRAlpha and PDGFRBeta can each form heterodimers with EGFR, which is also activated by PDGF. Various cells differ in the total number of receptors present and in the receptor subunit composition, which may account for responsive differences among cell types to PDGF binding. Ligand binding induces receptor dimerization and autophosphorylation, followed by binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules, such as GRB2, Src, GAP, PI3 kinase, PLCGamma, and NCK. A number of different signaling pathways are initiated by activated PDGF receptors and lead to control of cell growth, actin reorganization, migration, and differentiation.

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SKU: 74327397550

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4.3 ★★★★★
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Nicholas
Port Orchard, US
★★★★★ 5
Soooo cute & girly!
Color: Pastel Zigzag, Color: Pastel Zigzag
This cute coral and white pickleball paddle set is perfect for beginners or casual games. The paddles feel sturdy and well made, and the color combo is really fun and stylish. I also love that it comes with two different types of balls, so you’re ready to play right away. The compact carrying bag is a great bonus too — it keeps everything organized and is easy to bring to the court.
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Reviewed in the United States on March 14, 2026
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PS5Gamer
Bozeman, US
★★★★★ 5
No complaints at all
Color: Black
Great paddles, great value
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Reviewed in the United States on April 3, 2026
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Graftedin60
Los Angeles, US
★★★★★ 3
Meh
Color: Black
Ok paddles. Coach said not really the best for pickleball.
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Reviewed in the United States on March 22, 2026
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Jeff Cluff
Lowell, US
★★★★★ 5
What I expected
Color: Black
Exactly what I expected
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Reviewed in the United States on April 2, 2026
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Darius W.
Massapequa, US
★★★★★ 5
Very nice grip
Color: Black
New to pickleball but loving every minute of it
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Reviewed in the United States on February 23, 2026

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