SKU: 45998975852

TEAD3 His Tag Protein, Human

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Description

TEAD3 His Tag Protein, HumanProduct Specification Species Human Synonyms DTEF1; ETFR 1; ETFR 1; TEAD5; TEF 5 Accession Q99594 Amino Acid Sequence Arg218 Asp435, with N 8*HIS Expression System E. coli Molecular Weight 27kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Liquid Storage Buffer 20mTris, 300mNaCl, 20% glycerol, 5mM DTT, pH8. 0 Stability & Storage 12 months from date of receipt, lyophilized powder stored

Product Specification


Species Human
Synonyms DTEF1; ETFR 1; ETFR 1; TEAD5; TEF 5
Accession Q99594
Amino Acid Sequence Arg218-Asp435, with N-8*HIS
Expression System E.coli
Molecular Weight 27kDa (Reducing)
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Liquid
Storage Buffer 20mTris, 300mNaCl, 20% glycerol, 5mM DTT, pH8.0
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Yi Jin 1, Angela F Messmer-Blust(2011)Trends Cardiovasc Med.21:1

Background

The transcriptional enhancer factor (TEF) multigene family is primarily functional in muscle-specific genes through binding to MCAT elements that activate or repress transcription of many genes in response to physiological and pathological stimuli. Among the TEF family, TEF-1, RTEF-1, and DTEF-1 are critical regulators of cardiac and smooth muscle-specific genes during cardiovascular development and cardiac disorders including cardiac hypertrophy. Emerging evidence suggests that in addition to functioning as muscle-specific transcription factors, members of the TEF family may be key mediators of gene expression induced by hypoxia in endothelial cells by virtue of its multidomain organization, potential for post-translational modifications, and interactions with numerous transcription factors, which represent a cell-selective control mediator of nuclear signaling.

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SKU: 45998975852

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4.7 ★★★★★
Based on 29 reviews
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Ryan Miles
Whiting, US
★★★★★ 5
Clean Look, Super Comfortable – Instantly a Favorite
Size: 9.5, Color: White Leather
These sneakers are exactly what I was looking for—sleek, minimal, and incredibly comfortable right out of the box. The white leather looks sharp and pairs easily with everything from jeans to chinos, even dressed-down office wear. What surprised me most was the comfort. The sole is lightweight with just the right amount of cushioning, making them perfect for walking around all day. I’ve worn them on long city days and never felt sore or tired. They fit true to size (I’m a 9.5 and they’re spot on), and the quality feels premium. If you're after a versatile white sneaker that balances style and comfort, these are 100% worth it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 29, 2025
A
Verified Purchase
Alain
Whiting, US
★★★★★ 5
Comfortable
Size: 10.5 Wide, Color: Black Leather/Black
Very comfortable shoes, you feel like walking on clouds
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Reviewed in the United States on April 26, 2026
G
Verified Purchase
Gene and Karen
Omaha, US
★★★★★ 3
Not for all surfaces.
Size: 11.5 Wide, Color: Black Leather/Optic White
The sneakers look great and are comfortable on flat, smooth surfaces. Warning: The sole is very flexible and not well cushioned so a walk on rough or uneven surfaces can become uncomfortable quickly. Just understand the limitations.
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Reviewed in the United States on June 1, 2026
B
Verified Purchase
BBZ
Bozeman, US
★★★★★ 5
Very nice, but sizing is inconsistent
Size: 10 Wide, Color: Ivory/White/British Tan
All of these Cole Haan shoes are extremely well made and I like the styling. On the other hand, the sizing is very inconsistent and you may end up having to do a lot of returns trying to find the right size. Then if you get a different color of it, you may find the sizing different yet again. If you find your right zie, they are really nice shoes at a very reasonable price for the quality.
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Reviewed in the United States on February 6, 2026
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Verified Purchase
Lofidelityrockr
New York, US
★★★★★ 5
I love this brand. These shoes look and fit great!
Size: 13 Wide, Color: Black/White/Black
I love wearing Cole Haan shoes. This is the second pair I’ve owned and the style just gets me. I’ve worn these to work at a great professional job every day, not just casual Friday. I wear these when I head out shopping or to dinner. They are functional, comfortable, built for regular and bigger wider feet and comfortable. I am 6 feet tall and my feet have changed size over the years to me needing a wider shoe to relieve pressure on my toes and front wide porting of my foot. So the 13W feels great and still walks the same as a regular 14 but more comfort for me. They look amazing and qualify in some offices as dress shoes (depending on company rules they will justify a sneaker as a shoe with the tan colored “gum” sole as a sneaker) so check company policy. The black sole on this makes it look more dressy. I am switching out the laces to match my previous Cole Haan because I think the white shoelaces look better. As an adult, aside from my Kenneth Cole boots Reaction boots and Doc Marten’s these are the only shoes I will pay 3 digits for. This looks like skater shoes but with a more mature look.
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Reviewed in the United States on December 19, 2025

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