SKU: 39707577907

SkinCeuticals® Metacell Renewal B3 Cream 50mL

Sale price$168.30 Regular price$187.00
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Description

SkinCeuticals® Metacell Renewal B3 Cream 50mLMetacell Renewal B3 utilizes a patent pending aqueous emulsion to deliver a high concentration of 5% niacinamide (vitamin B3) combined with a firming tripeptide concentrate, and 15% pure glycerin to address early signs of photoaging. While signs of photoaging appear at different intensities according to skin biology, lifestyle, geography, sun protection behavior, and skincare regimen, they have a multiplicative effect, creating a prematurely aged

Metacell Renewal B3 utilizes a patent-pending aqueous emulsion to deliver a high concentration of 5% niacinamide (vitamin B3) combined with a firming tripeptide concentrate, and 15% pure glycerin to address early signs of photoaging.

While signs of photoaging appear at different intensities according to skin biology, lifestyle, geography, sun protection behavior, and skincare regimen, they have a multiplicative effect, creating a prematurely-aged appearance.

This comprehensive daily emulsion visibly improves these early signs of photoaing by increasing cell turnover to resurface skin, help reclarify and even skin tone, and improve the appearance of wrinkles and surface elasticity.

How To Use

Twice daily, massage one to two pumps into a thin, even layer onto the entire face, neck, and chest.

Key Benefits

  • Helps stimulate skin renewal.
  • Strengthens skin’s natural moisture barrier.
  • Reduces the appearance of discolouration and blotchiness.
  • Intense hydration in a lightweight formula which doesn’t leave skin feeling heavy or sticky.
  • Helps improve the appearance of skin’s firmness.

Visible Results

Significant improvement in signs of photoaging with a 15% improvement in the appearance of radiance and luminosity, 20.9% improvement in the appearance of fine lines, and 10.9% improvement in the appearance of firmness. (Protocol: A dermatologist-controlled 12-week clinical on 56 female subjects, ages 40-55. Subjects applied Metacell Renewal B3 twice daily. Subjects also used SkinCeuticals Gentle Cleanser and Physical UV Defense SPF 30 as needed). Individual results may vary.

Statistically significant improvement - at week 4, 4% improvement in skin tone (clarity); 4% improvement in radiance/luminosity; 5% improvement in skin texture/smoothness; 8% improvement in fine lines; 3% improvement in firmness/tightness. At week 12, 14% improvement in skin tone (clarity);15% improvement in radiance/luminosity; 14% improvement in skin texture/smoothness; 21% improvement in fine lines; 11% improvement in firmness/tightness. (12 week clinical study on 56 subjects. Subjects applied Metacell Renewal B3 twice daily)

Science & Proof

In an optical skin imaging study, Metacell Renewal B3 demonstrated a significant reduction in redness, contributing to enhanced clarity and an improved appearance of skin texture.

Metacell Renewal B3 is proven to be safe to use immediately post-Intense Pulsed Light (IPL) treatment. Significantly increase hydration to skin when compared to a placebo. Strengthened the skin barrier, which IPL can disrupt, by significantly improvement trans-epidermal water loss.

Protocol: 8-week study on 25 women, aged 30-59 with mild to moderate facial photodamage. Metacell Renewal B3 and its placebo were applied to the face in a split-face, randomized manner, post-IPL procedure (at baseline and week 4), twice a day for 53 days in the morning and evening).

Ingredients

  • 5% niacinamide (vitamin B3): Niacinamide , also known as vitamin B3, helps reduce the appearance of skin discolouration and strengthens skin’s moisture barrier
  • 2.5% firming tri-peptide concentrate:A blend of powerful peptides helps maintain skin’s natural hyaluronic acid levels, reduces the look of fine lines, and improves the appearance of firmness
  • 15% pure glycerin:This humectant has water-binding properties that delivers intense hydration without a heavy or tacky feel 

855156 47 - AQUA / WATER, GLYCERIN, DIMETHICONE,NIACINAMIDE, PROPANEDIOL, DIMETHICONE/PEG-10/15 CROSSPOLYMER,METHYLSILANOL/SILICATE CROSSPOLYMER, SODIUM CHLORIDE,POLYMETHYLSILSESQUIOXANE, PHENOXYETHANOL, MICROCRYSTALLINECELLULOSE, CI 77163/BISMUTH OXYCHLORIDE, CHLORPHENESIN, CAPRYLYL GLYCOL, SODIUM CITRATE, ETHYLHEXYL HYDROXYSTEARATE, PEG-10DIMETHICONE,DISODIUM EDTA,CELLULOSE GUM,LAMINARIA DIGITAL EXTRACT, ADENOSINE, DIPROPYLENE GLYCOL, CITRUS AURANTIUM AMARAFLOWER OIL /BITTER ORANGE FLOWER OIL, MELALEUCA VIRIDIFLORA LEAF OIL, TETRADECYL AMINOBUTYROYLVALYLAMINOBUTYRIC UREA TRIFLUOROACETATE,LINALOOL,CYMBOPOGON SCHOENANTHUS OIL,MAGNESIUM CHLORIDE, CITRAL, TOCOPHEROL, LIMONENE, PELARGONIUM GRAVEOLENS FLOWER OIL,D166367/6.

Please be aware that ingredient lists for the products of our brand are updated regularly. Please refer to the ingredient list on your product package for the most up to date list of ingredients to ensure it is suitable to your personal use.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 39707577907

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4.6 ★★★★★
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V
Verified Purchase
Valarie Amundsen
Natrona Heights, US
★★★★★ 5
Chew
Size: X-Small, Color: Ring Bone
My dog loves this little chewy bone and it’s good for her teeth. That was very cheap on a sale. It’s worth giving it a try highly recommend it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 11, 2026
P
Verified Purchase
princeton von d
Waukegan, US
★★★★★ 3
Chicken Flavor Good, But 🔄 Rotation-Resistant✖; Best for Simpler Chewers
Size: X-Small, Color: Ring Bone, Size: X-Small, Color: Ring Bone
🐾 Hi, I’m PVD; plush sophisticate, chew critic, and active curator of rotational toy relevance. This ring bone and I never fully bonded. I sampled it maybe five times in my entire puppyhood before quietly returning it to the bin (with a single judgmental glance). Still, it does have value for the right pup. ⭐ Why I originally wanted to love it: ✔️ XS size works well for very young puppies ✔️ Chicken flavor lasts impressively long ✔️ Freezing offers temporary gum relief ✔️ Durable and safe; no odd odors or shredding 🌀 Why it’s now a respectful 3-star chew in my rotation: ✘ Never became a go-to toy (5 uses max in my life) ✘ Ring shape felt awkward, not natural or chic; hard to grip and maneuver ✘ Texture too tame vs. nubs or detailed chew surfaces ✘ When I was smaller, I much preferred the Nylabone Baby Blue Bone Chew Toy with nubs (my personal classic), and have since matured into nightly Nylabone “Nubz” edible bones This Ring Bone is Best For: • Very young puppies with minimal chew preferences • Dogs who like simple textures and circular shapes • Those just starting enrichment chew play • Freezer treat rotations (briefly) 🚫 Not ideal for: picky pups, advanced chewers, or dogs who analyze toy ergonomics (like myself). 📝 Final Re-Barks: A strong, well-made chew, but lacked the intrigue to make my permanent rotation. Works for basic chew enjoyment; not for pups with elevated taste or toy ambition. — PVD (Chew Strategist, Textural Analyst & Aspire-to-Vine Reviewer 🐶💼)
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 17, 2025
K
Verified Purchase
Kaitlynne Lynch
Dallas, US
★★★★★ 5
Puppy loves it!
Size: X-Large, Color: Teething Bone, Size: X-Large, Color: Teething Bone
My small puppy loves this bone! I originally purchased this for a larger dog, but my small 10 pound puppy loves it more. It’s good quality and a softer material for puppies!
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Reviewed in the United States on May 10, 2026
J
Verified Purchase
Jesse Arner
Alexandria, US
★★★★★ 4
A hit, but could be stronger
Size: Medium, Color: Ring Bone, Size: Medium, Color: Ring Bone
Gave this to my 11 week old pittie, and she did significant damage within 15 mins. She left a pile of chewed bits on the couch but thankfully didn't eat them. Definitely don't leave unsupervised. That said, she LOVED it and it seemed to help her teething gums so, I'm still giving it a 4/5 Puppy pics for tax
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Reviewed in the United States on June 3, 2026
A
Verified Purchase
Amazon Customer
New York, US
★★★★★ 5
FOR SHORT TIME USE
Size: X-Small, Color: Ring Bone
My puppies love this. After a couple of weeks, it is worn so I throw it out and buy another since it's reasonably priced. I don't want them to actually ingest a chunk of this.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 11, 2026

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