SKU: 51744310902

YK-11 Poeder, 1gr

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Description

YK-11 Poeder, 1grYK 11 Wat is YK 11? YK 11, ook bekend als myostine, is een selectieve androgeenreceptormodulator (SARM) die klinisch is aangetoond de androgeenreceptor gedeeltelijk te activeren en tegelijkertijd te functioneren als een myostatineremmer. Onderzoek en eigenschappen Een studie van Lee et al. onderzocht YK 11 als een potentieel middel voor spieropbouw en spierbehoud in situaties van sepsis. In het onderzoek kregen muizen tien dagen lang twee

YK-11

Wat is YK-11?

YK-11, ook bekend als myostine, is een selectieve androgeenreceptormodulator (SARM) die klinisch is aangetoond de androgeenreceptor gedeeltelijk te activeren en tegelijkertijd te functioneren als een myostatineremmer.

Onderzoek en eigenschappen

Een studie van Lee et al. onderzocht YK-11 als een potentieel middel voor spieropbouw en spierbehoud in situaties van sepsis. In het onderzoek kregen muizen tien dagen lang twee verschillende doses YK-11 toegediend (oraal, 350 mg/kg en 700 mg/kg), waarna ze blootgesteld werden aan een peritoneale injectie van E. coli-bacteriën.

Het onderzoek toonde aan dat YK-11 de werking van myostatine remt — een hormoon dat spiergroei beperkt (bron). Behandelde muizen behielden hun lichaamsmassa tijdens ziekte en hadden een gunstigere vet-spierverhouding ten opzichte van de controlegroep.

Na blootstelling aan systemische E. coli konden de behandelde muizen spiermassa in rug en dijen beter herstellen. Hun spiercellen waren bovendien beter bestand tegen atrofie.

Effecten op immuunrespons en organen

Naast effecten op spiermassa, had YK-11 ook impact op de immuunreactie. Behandeling resulteerde in een verlaging van endotoxines en ontstekingsmarkers in de longen. Ook biomarkers voor orgaanschade — zoals AST, ALT en BUN — waren verlaagd.

De eliminatie van schadelijke bacteriën uit organen werd verbeterd bij muizen die met YK-11 waren behandeld (bron), en het overlevingspercentage na sepsis bleek hoger tot aan het 72-uurmerk.

🧪 Inhoud

Het potje bevat 1 gram puur YK-11 poeder.
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📄 Disclaimer

Dit materiaal wordt uitsluitend verkocht voor gebruik in laboratoriumonderzoek. Verkoopvoorwaarden zijn van toepassing. Niet voor menselijke consumptie, noch voor medisch, diergeneeskundig of huishoudelijk gebruik. Maak uzelf vertrouwd met onze DISCLAIMER voordat u bestelt.

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SKU: 51744310902

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4.4 ★★★★★
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Isabelle
Boise, US
★★★★★ 4
Interesting
Format: Kindle
This was a very captivating book once you got into it thoroughly. But the third person perspective was a bit hard to get used to. But as you got into it and followed the different characters, it was interesting and filled with intrigue, conflict and forbidden love. I can’t wait to read the next one and to complete the series.
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Reviewed in the United States on November 12, 2022
E
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❈ Elizabeth ❈ | Breakawayreads
Lexington, US
★★★★★ 5
Fallen Angels, fae, vampires, oh my!
Format: Kindle
Rating: 4.5 | Spice: 2 (but a good slow-burn) • Main Characters: Huntyr and Wolf • I couldn’t wait to read this book; there was so much hype about it! And there was no doubt why. I fell in love with the characters and the plot itself. This book is mainly plot driven more than friction driven but it’s easy to follow along with. The characters are fun, easily understood. The main setting is at an academy where both the main characters are going through trials and building strength for the final test, The Transcendent. There are fantastic side characters as well. I loved the camaraderie between Huntyr and her friends. But we don’t like Lanson. 😆 We do have some plot twists that come into play throughout the book. Secrets and betrayal to be seen. I did adore Wolf and Huntyr’s relationship. It was a classic slow burn trope. They didn’t hit it off fast, but in time their feelings grew. I loved their banter, so sexy. Wolf is your next book boyfriend; Huntyr is your next vampire assassin independent bad-a*s female. Themes include loyalty, trust, self-discovery, a true slow burn romance. Side note: book ends on a angsty cliffhanger! • Emily, thank you for writing this awesome novel and I cannot wait to devour Book 2, Blood So Brutal! 😍 • Happy reading, my lovelies! xo
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Reviewed in the United States on January 21, 2024
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MelsABookworm
Waukegan, US
★★★★★ 4
“My heart bows to you and you only, Huntress.”
Format: Kindle
3.5 🌟 This book popped up in my KU recommended reading suggestions and the synopsis sounded like what I was in the mood for. I'm so glad I took a chance on it. I went into this knowing absolutely nothing about it and ended up really liking it. I love when this happens. The main characters are likeable and I easily found myself rooting for them. There is a mystery element to each of their backstories that I enjoyed watching unfold and can't wait to get more of. Wolf, in particular, has me fixated. Love him. I found this to be an entertaining, addictive read with a plot that moves along at a good pace. It reads so easily I found myself very reluctant to put it down. Lots of twists and turns and the angst is there. A good set up for the next book to come, for sure. My issues with this book....the dialogue feels a bit juvenile at times and there is a repetitive over use of a particular word phrasing that I found myself giving the ole eye-roll to. There are, without a doubt, some pretty cliche moments that gave me a bit of the cringe. I think this could've certainly 100% benefited from more depth regarding the world building. Perhaps the world building was sacrificed to keep the pacing quick? Just a guess. Also, the lack of consistency of character for the FMC was really evident and so she feels quite illogical at times. Overall, this was a fun and enjoyable read that hit the spot well enough for me. That ending certainly has me impatiently pining for book 2!
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Reviewed in the United States on June 18, 2024
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Amazon Customer
Charlottesville, US
★★★★★ 3
Interesting take on the genre
Format: Kindle
True rating: 3.25 ⭐️ I enjoyed the fresh take on the genre. The best way I could describe the setting and world is an apocalyptic dystopian version of Farie where vampires, fae, and angles struggle to survive in what is left of the world. It was definitely interesting throwing the academy/hunger games aspect into this world as well. Even though I guessed the final reveal early on in the book, I kept hoping I was wrong, and it would take a surprising turn. While the "plot twists" were a bit predictable to me, I still enjoyed the ride this book took me on. Another downfall for me was the plot holes in the world building... I.E. if society has fallen and the world is in the aftermath of war, how are there trains running around the world? Just to take young adults to the trials to get into the golden city? How is the train maintained, the tracks clear, etc? However, I did enjoy the FMC & MMC and thought they were fleshed out nicely. I also enjoyed the side characters but wish some were developed more like Ashalin (sp?). I do find myself rooting for the MCs to succeed and find happiness together, which is obviously an important aspect for romantasy. Overall, was this an earth-shattering, mind-bending, terrific piece of literature? No. But was it the worst thing I've read this year? Also, no. This book has, to me, the bones of a great read & just needs a bit more to push it from an alright book to a great book. Overall ratings: Plot- 3.5⭐️ World building 3⭐️ Spice 2.5 🌶🌶 Main characters 4 ⭐️ Supporting characters 3.5⭐️
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Reviewed in the United States on May 12, 2024
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Irene zamora
Belleville, US
★★★★★ 5
great book
Format: Kindle
I am really excited to meet the author at the book retreat this month. I really enjoyed this world that she built and most of the female main character Huntress is so awesome. She goes through a lot in this book and the ending; wow! I wouldn't have even guessed. I highly recommend everyone to read this book. I have been so lucky this year that almost all the books I have read have been, so far, 5 out 5 stars.
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Reviewed in the United States on June 2, 2026

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